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Isotretinoin is a form of vitamin A. It reduces the amount of oil released by oil glands in your skin, and helps your skin renew itself more quickly. Isotretinoin is used to treat severe nodular acne that has not responded to other treatments, including antibiotics.
Always take isotretinoin with a full glass of water to prevent the capsule from melting in your esophagus (food pipe), causing irritation. Do not chew or suck on the capsule. Swallow it as quickly as possible. Take this medication for the entire length of time prescribed by your doctor.
Dry skin and eyes Muscle aches
Accutane Overview - Patient Information: Side Effects. SIDE EFFECTS: Dry lips and mouth, minor swelling of the eyelids or lips, crusty skin, nosebleeds, upset stomach, or thinning of hair may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
The recommended dosage range for Accutane is 0.5 to 1.0 mg/kg/day given in two divided doses with food for 15 to 20 weeks. In studies comparing 0.1, 0.5, and 1.0 mg/kg/day,8 it was found that all dosages provided initial clearing of disease, but there was a greater need for retreatment with the lower dosages.
Isotretinoin (13-cis retinoic acid) is a vitamin-A derivative (retinoid). The liver naturally makes small quantities of isotretinoin from vitamin-A, but the drug we prescribe is made synthetically. Isotretinoin was developed in the 1950s, but only started being used in the mid 1970s.
A standard course of therapy is 16 to 20 weeks. At the end of 16 weeks, about 85% of patients are clear. The beneficial effects of Accutane do not stop when the drug is discontinued. A further reduction of acne lesions and improvement of scarring is seen for months after treatment has stopped.
Common side effects include:
Voice changes Headache
Accutane is linked to serious side effects like birth defects, thoughts of suicide, depression and bowel disorders. ... Although the drug was hailed by dermatologists as a breakthrough treatment for patients with severe acne, Accutane's dangerous side effects affected thousands of patients during the past 30 years
Bleeding or swollen gums Fatigue
The bad news is that if it isn't used correctly there can be serious side effects. Accutane can cause severe birth defects. ... Note, Accutane is NOT anabolic steroids, and should not be considered in the same drug category. It's an anti-acne medication.
Milder Side Effects of Accutane
Acne. So your dermatologist recommended you start taking isotretinoin (AKA Accutane) for your acne. But you're nervous because you've heard that isotretinoin medications can cause depression and suicidal thoughts. It's understandable to be a bit unnerved by the idea, and it's smart to do your research.
Accutane is used in the treatment of acne; rosacea; granuloma annulare; melanoma, metastatic; acute nonlymphocytic leukemia and belongs to the drug classes miscellaneous antineoplastics, miscellaneous uncategorized agents. ... Accutane 10 mg is not a controlled substance under the Controlled Substance Act (CSA).
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